Docking protein 2 binds p120 ( RasGAP ) from CML cells.
2.
The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family.
3.
GAB proteins were one of the first docking proteins identified in the mammalian signal transduction pathway.
4.
LMDs are docking proteins that function as platforms mediating interaction between different signaling pathways and assisting with signal integration.
5.
"' Signal recognition particle ( SRP ) receptor "', also called docking protein, is a membrane of the endoplasmic reticulum.
6.
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia ( CML ) patients in the chronic phase.
7.
The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling.
8.
GAB2 is a docking protein with a conserved, folded PH domain attached to the membrane and a large disordered region, which hosts interactions with signaling molecules.
9.
In this pathway, recruitment of a guanine nucleotide exchange factor by the adaptor and docking proteins leads to activation of a membrane-associated G-protein known as Raf.
10.
GAB2 along with many other adaptor, scaffold, and docking proteins, was discovered in the mid-1990s during the isolation and cloning of protein tyrosine kinase substrates and association partners.
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